Download Aging: Modern Theories and Therapies (New Biology) by Joseph Panno PDF

By Joseph Panno

Makes an attempt to appreciate the getting older method have generated a lot of theories yet few functional remedies. conventional treatments deal with age-related illnesses similar to melanoma and arthritis yet don't opposite the getting older procedure itself. a typical pattern in gerontology is to go looking for genes that experience a demonstrable influence on lifespan, the so-called durability genes. Many such genes were pointed out, and even supposing the manipulation of those genes doesn't cease the getting older approach, they supply many worthwhile insights into the mobile mechanisms of getting older. extra lately, curiosity has became to using cloning expertise, stem mobilephone research, and genetic manipulation which will produce a good rejuvenation treatment for cells and the physique as an entire.

getting older, Revised version describes the sector of gerontology and the various theories that scientists have constructed through the years to give an explanation for the age-related alterations that happen in approximately all animals.

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Extra resources for Aging: Modern Theories and Therapies (New Biology)

Sample text

In 1882 August Weismann, a German embryologist, proposed the first theory of senescence that tried to link life span to natural selection. Weismann argued that the termination of life may have a selective advantage, and that there is a connection between a species’ life span and its ecological niche, body size, and intelligence. During this same period German chemists were developing the first biochemical techniques that allowed Hans Krebs to work out the 16 AGING cyclic details of energy metabolism that now bear his name (Krebs cycle, also known as the citric acid cycle).

34 AGING 5. Many centenarian women have a history of bearing children later in life (ages 35 to 40), suggesting that their reproductive system is aging at a lower rate than the general population. 6. Metastatic cancer is relatively rare among this group of people. 7. About 88 percent of centenarians delay or escape the development of cardiac disease, stroke, and diabetes. 8. More than 90 percent of centenarians are functionally independent. 9. Exceptional longevity runs in families. Aging Mosaics The difference between modern and classical aging suggests that the human population is an aging mosaic, consisting of individuals that age at different rates.

6. Metastatic cancer is relatively rare among this group of people. 7. About 88 percent of centenarians delay or escape the development of cardiac disease, stroke, and diabetes. 8. More than 90 percent of centenarians are functionally independent. 9. Exceptional longevity runs in families. Aging Mosaics The difference between modern and classical aging suggests that the human population is an aging mosaic, consisting of individuals that age at different rates. Aging mosaics can also be found at the level of the cells and tissues and were implied by the neuroendocrine theory of the aging process, first proposed in the 1970s.

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