By Icon Health Publications
This can be a 3-in-1 reference ebook. It offers a whole scientific dictionary overlaying thousands of phrases and expressions when it comes to arsenic. It additionally offers wide lists of bibliographic citations. ultimately, it presents details to clients on the way to replace their wisdom utilizing numerous web assets. The booklet is designed for physicians, clinical scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to familiarize yourself with learn devoted to arsenic. in case your time is effective, this publication is for you. First, you won't waste time looking out the net whereas lacking loads of appropriate details. moment, the publication additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing 1000s of websites.
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Extra resources for Arsenic - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
The activation of the three major MAP- kinase pathways, ERK1/2, JNK1/2, and -38 following exposure of the BLL-cell lines to the environmental pollutants arsenic and cadmium, and selected drugs that share with these metals the ability to perturb mitochondrial function will be examined. Specific chemical inhibitors and dominant negative strategies will be used to establish causality between activation of these kinases and induction of apoptosis in susceptible cell lines. In addition, the roles that these kinase pathways play in acquired sensitivity to apoptosis induction in resistant cell lines following low-level chemical exposure will also be studies.
There are 4 biomedical projects: 1) Epigenetic Effects on Individual Susceptibility to Heavy Metal and Polycyclic Aromatic Hydrocarbon-induced DNA damage (E. Tang); 2) 26 Arsenic Detection of Cr-DNA Adducts in Human Cells (M. Costa); 3) Metal-induced Inflammatory Factors, Oxidative Stress, and Suppression of Their Effects (K. Frenkel); 4) Identification and Genetic Analysis of the Human Arsenic Efflux Pump (T. Rossman). There are 3 non-biomedical projects: 1) Mechanisms of Resistance of Aquatic Vertebrate Populations to Mixtures of Aromatic Hydrocarbon and Metal Contaminants (I.
Proteolytic reactivation by metal chelators will be assessed. GaAs' interference with the transport sorting signal of cathepsins will be examined. Fifth, a correlation between cytokine production and altered macrophage antigen processing will be investigated. A panel of cytokines with varying functions will be measured by ELISA. Mutant nude mice that lack functional T cells, an important cytokine source, will be exposed to GaAs, and antigen processing by alveolar and splenic macrophages will be determined.